You can’t build if you don’t dwell first. This sentence is counterintuitive. It is usually thought that first you build, and then you dwell where you have built. But if you don’t dwell where you want to build, you may not understand the landscape, and the building will be weak or crippled.In Latin, “to dwell” is habitare, which comes from the verb habere, “to own.” The phrase “You can’t build if you don’t dwell first” can be considered the leitmotif of (...) the “Yes to Life” Congress, held in Vatican City in 2019. The goal of the conference was to overcome prejudices and preconceptions about the correct approach to end-of-life cases in perinatology. Overcoming prejudices about this particular stage of life is hard in... (shrink)

A estrutura das antinomias lógicas, redescobertas e reformuladas por Frege e Russell no começo do século XX, consiste num movimento circular que é, ao mesmo tempo, autoflexivo e negativo. Surge, aí, um perpétuo oscilar entre o Sim e o Não, em certos casos, entre verdade e falsidade. Os Lógicos resolvem o problema pela distinção de tipos ou níveis linguagem. Alguns filósofos - Kulenkampff, Kesselring, Wandschneider – pensam ter aí encontrado o mecanismo central que move a Dialética. Procura-se aqui mostrar que (...) estão, pelo menos em grande parte, equivocados. Dialética é algo bem mais simples e mais amplo. (shrink)

Trait emotional intelligence concerns our perceptions of our emotional abilities, that is, how good we believe we are in terms of understanding, regulating, and expressing emotions in order to adapt to our environment and maintain well-being. In this article, we present succinct summaries of selected findings from research on the location of trait EI in personality factor space, the biological underpinnings of the construct, indicative applications in the areas of clinical, health, social, educational, organizational, and developmental psychology, and trait EI (...) training. Findings to date suggest that individual differences in trait EI are a consistent predictor of human behavior across the life span. (shrink)

Mucopolysaccharidosis type I (MPS I) is a rare lysosomal storage disorder treated with bone marrow transplantation or enzyme replacement therapy with laronidase, a high-cost orphan drug. Laronidase was approved by the US Food and Drug Administration and the European Medicines Agency in 2003 and by the Brazilian National Health Surveillance Agency in 2005. Many Brazilian MPS I patients have been receiving laronidase despite the absence of a governmental policy regulating access to the drug. Epidemiological and treatment data concerning MPS I (...) are scarce. This study aims to present a demographic profile of Brazilian patients with MPS I, describe the routes of access to laronidase in Brazil, and discuss associated ethical issues relating to public funding of orphan drugs. (shrink)

Since at least Hume and Kant, philosophers working on the nature of aesthetic judgment have generally agreed that common sense does not treat aesthetic judgments in the same way as typical expressions of subjective preferences—rather, it endows them with intersubjective validity, the property of being right or wrong regardless of disagreement. Moreover, this apparent intersubjective validity has been taken to constitute one of the main explananda for philosophical accounts of aesthetic judgment. But is it really the case that most people (...) spontaneously treat aesthetic judgments as having intersubjective validity? In this paper, we report the results of a cross‐cultural study with over 2,000 respondents spanning 19 countries. Despite significant geographical variations, these results suggest that most people do not treat their own aesthetic judgments as having intersubjective validity. We conclude by discussing the implications of our findings for theories of aesthetic judgment and the purpose of aesthetics in general. (shrink)

Dialéticos e analíticos não se entendemporque falam línguas com sintaxes parcialmentediferentes. Não obstante esta diferença, hátrês princípios básicos que regem e estruturamtanto a lógica dialética como a lógica analítica: osprincípios de identidade, de diferença e de coerênciauniversal. Os mesmos três princípios regemtambém a natureza em seu processo de evoluçãoe constituem o indivíduo e a espécie,as mutações por acaso ea seleção natural.

Genomic instability is a hallmark of cancer. Cancer cells that exhibit abnormal chromosomes are characteristic of most advanced tumours, despite the potential threat represented by accumulated genetic damage. Carcinogenesis involves a loss of key components of the genetic and signalling molecular networks; hence some authors have suggested that this is part of a trend of cancer cells to behave as simple, minimal replicators. In this study, we explore this conjecture and suggest that, in the case of cancer, genomic instability has (...) an upper limit that is associated with a minimal cancer cell network. Such a network would include (for a given microenvironment) the basic molecular components that allow cells to replicate and respond to selective pressures. However, it would also exhibit internal fragilities that could be exploited by appropriate therapies targeting the DNA repair machinery. The implications of this hypothesis are discussed. (shrink)

Rapid individual cognitive phenotyping holds the potential to revolutionize domains as wide‐ranging as personalized learning, employment practices, and precision psychiatry. Going beyond limitations imposed by traditional lab‐based experiments, new efforts have been underway toward greater ecological validity and participant diversity to capture the full range of individual differences in cognitive abilities and behaviors across the general population. Building on this, we developed Skill Lab, a novel game‐based tool that simultaneously assesses a broad suite of cognitive abilities while providing an engaging (...) narrative. Skill Lab consists of six mini‐games as well as 14 established cognitive ability tasks. Using a popular citizen science platform (N = 10,725), we conducted a comprehensive validation in the wild of a game‐based cognitive assessment suite. Based on the game and validation task data, we constructed reliable models to simultaneously predict eight cognitive abilities based on the users’ in‐game behavior. Follow‐up validation tests revealed that the models can discriminate nuances contained within each separate cognitive ability as well as capture a shared main factor of generalized cognitive ability. Our game‐based measures are five times faster to complete than the equivalent task‐based measures and replicate previous findings on the decline of certain cognitive abilities with age in our large cross‐sectional population sample (N = 6369). Taken together, our results demonstrate the feasibility of rapid in‐the‐wild systematic assessment of cognitive abilities as a promising first step toward population‐scale benchmarking and individualized mental health diagnostics. (shrink)

Boundary extension is a memory phenomenon in which an individual reports seeing more of a scene than they actually did. We provide the first examination of boundary extension in individuals diagnosed with depression, hypothesising that an overemphasis on pre-existing schema may enhance boundary extension effects on emotional photographs. The relationship between boundary extension and overgeneralisation in autobiographical memory was also explored. Individuals with (n = 42) and without (n = 41) Major Depressive Disorder completed a camera paradigm task utilising positive, (...) negative, and neutral stimuli. Across all participants, positive (d = 0.37) and negative (d = 0.66) stimuli were extended more than neutral stimuli. This effect did not differ between depressed and never-depressed participants. Across all participants, images containing objects were extended more than images containing faces. An association was also evident between extension effects in memory for perceptual space and extensions of autobiographical memory across time. (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

The influx of new groups into society, such as recently established religious groups whose practices differ from societal norms, may disturb relatively stable communities. This instability is exacerbated if these practices contravene long-held fundamental societal tenets, such as the protection of children. This situation now exists in Mexico, where the country's traditional Catholic and secular values clash with those of a religion introduced from the United States, Jehovah's Witnesses. The focal point for these clashes, as it has been elsewhere, is (...) in the bioethics arena. (shrink)

The End of Materialism: How Evidence of the Paranormal Is Bringing Science and Spirit Together by Charles T. Tart. Philosophy of Personal Identity and Multiple Personality by Logi Gunnarsson. Eusapia Palladino and Her Phenomena by Hereward Carrington. Can the Mind Survive beyond Death? In Pursuit of Scientific Evidence by Satwant K. Pasricha. Morphic Resonance: The Nature of Formative Causation by Rupert Sheldrake. A New Science of Life: The Hypothesis of Formative Causation by Rupert Sheldrake. “Why AI Is a Dangerous Dream,” (...) Opinion, Interview with Noel Sharkey by Nic Fleming. (shrink)

Recent research has shown that cultural, linguistic, and sociodemographic peculiarities influence the measurement of trait emotional intelligence. Assessing trait EI in different populations fosters cross-cultural research and expands the construct’s nomological network. In mental health, the trait EI of clinical populations has been scarcely researched. Accordingly, the present study examined the relationship between trait EI and key sociodemographic variables on Trait Emotional Intelligence Questionnaire datasets with mental healthcare patients from three different Spanish-speaking countries. Collectively, these datasets comprised 528 participants, 23% (...) from Chile, 28% from Peru, and 49% from Spain. The sociodemographic variables we used for trait EI comparisons were gender, age, educational level, civil status, and occupational status. Analyses involved Multigroup Exploratory Structural Equation Modelling and analysis of covariance. Our results revealed significant between-country differences in trait EI across the studied sociodemographic variables and interactions between these variables. Measurement invariance across the datasets was attained up to the scalar level regarding gender and education, although analyses on age, civil status, and occupation displayed non-invariance. The resultant psychometric evidence supports the suitability of the TEIQue-SF for the accurate cross-cultural assessment of trait EI in mental health settings. It also highlights the importance of incorporating trait EI into extant psychotherapeutic frameworks to enhance non-pharmacological treatment efficacy. (shrink)

The search for a systems‐level picture of metabolism as a web of molecular interactions provides a paradigmatic example of how the methods used to characterize a system can bias the interpretation of its functional meaning. Metabolic maps have been analyzed using novel techniques from network theory, revealing some non‐trivial, functionally relevant properties. These include a small‐world structure and hierarchical modularity. However, as discussed here, some of these properties might actually result from an inappropriate way of defining network interactions. Starting from (...) the so‐called bipartite organization of metabolism, where the two meaningful subsets (reactions and metabolites) are considered, most current works use only one of the subsets by means of so‐called graph projections. Unfortunately, projected graphs often ignore relevant biological and chemical constraints, thus leading to statistical artifacts. Some of these drawbacks and alternative approaches need to be properly addressed. (shrink)

This volume contains an English translation of Edmund Husserl’s first major work, the Philosophie der Arithmetik, (Husserl 1891). As a translation of Husserliana XII (Husserl 1970), it also includes the first chapter of Husserl’s Habilitationsschrift (Über den Begriff der Zahl) (Husserl 1887) and various supplementary texts written between 1887 and 1901. This translation is the crowning achievement of Dallas Willard’s monumental research into Husserl’s early philosophy (Husserl 1984) and should be seen as a companion to volume V of the Husserliana: (...) Collected Works series (Husserl 1994b), which already contained selected translations from Hua XII. As Willard re- marks on the inner cover of the volume, it is “a window on a period of rich and illuminating philosophical activity”, to which I wholeheartedly agree. Willard’s two volumes of translations open this window on the beginnings of Husserl’s philosophy for the English-speaking world. This earliest period of Husserl’s philosophy has often been unjustly ignored and Willard provides the English reader with an excellent starting point. Husserl’s first steps into phenomenology and the philosophy of logic and mathematics contain many promising seeds that will flower later on, in the Logische Untersuchungen and beyond. (shrink)

t. 1. Livres I à IV -- t. 2. Livres V à VII et Notes marginales de Nicolas de Cues.

The original article was published without open access and with the copyright notice indicating © Springer Nature B.V. The article is now open access with the copyright residing with the authors.

The relationship between attention and consciousness is one that is crucial for understanding perception and different types of conscious experience, and we commend this analysis of the topic by Pitts, Lutsyshyna, and Hillyard (2018). We have also examined this relationship closely (e.g., Montemayor & Haladjian, 2015) and would like to point out a few potential contradictions in the Pitts et al. paper that require clarification, particularly in the attempt to reconcile aspects of recurrent processing theory (RPT) with global neuronal workspace (...) theory (GNWT). This commentary addresses these points and introduces other considerations important for this topic. (shrink)

The Commentary on Plato's Parmenides by Proclus is the most important extant document on the interpretation of this enigmatic dialogue in antiquity, and has had a crucial influence on all subsequent readings. In Proclus' Commentary, the Parmenides provides the argumentative and conceptual framework for a scientific theology wherein all mythological discourse about the gods can be integrated. Its exposition was therefore the culmination of the curriculum of the Platonic school. This theological reading of the Parmenides persisted, through the medium of (...) Ficino, until the nineteenth century. Previously this important text was only accessible in the edition of V. Cousin. This new critical edition is based on an exhaustive study of both the Greek tradition and the medieval Latin translation. (shrink)

Bernardi Perini, G. Aceto italico e poesia luciliana: Hor. Sat. I 7.--Bernardinello, S. Bessarione riassume la Fisica di Aristotele.--Bottecchia, M. E. I Mechanicha di Aristotele nel Parisinus graecus 2507.--Bottin, L. La tradizione araba della Retorica di Aristotele e il problema dell'exemplar decurtatum.--Chiereghin, F. Analogie di struttura tra la metodologia della storiografia filosofica di Platone e di Kant.--Ciani, M. G. Poesia come enigma.--Degani, E. Hippon. fr. 40 Med.--Donaldi, F. Note preparatorie all'edizione dell'Encomio di Elena gorgiano nella traduzione latina inedita di Pietro (...) Bembo.--Fumarola, V. Euripide e la tetralogia della femminilità.--Gentilini, A. Una consolatoria inedita del Bessarione.--Ghinatti, F. I culti greci di Paestum.--Longo, O. Note all'Elena e alle Nuvole.--Lunelli, A. Solis rota.--Meschini, A. Su alcuni luoghi del Reso.--Mignucci, M. In margine al concetto aristotelico di esistenza.--Mioni, E. L'Antologia greca da Massimo Planude a Marco Musuro.--Pianezzola, E. Haurio=ferio, perfodio. Un calco omerico mediato dagli scolii.--Pontani, F. M. La distruzione di Melos di Ghiannis Ritsos.--Rinaldi Mioni, G. Aspetto verbale nel greco classico e strutturalismo.--Riondato, E. Problematicità semantica ed etica nell'Etica a Nicomaco.--Serra, G. Alcune osservazioni sulle traduzioni dall'arabo in ebraico e in latino del De generatione et corruptione di Aristotele e dello pseudo-aristotelico Liber de causis.--Traina, A. Convexo nutantem pondere mundum (Verg. Ecl. 4,50).--Valentini, R. La reintroduzione dell'onciale e la datazione dei manoscritti greci in minuscola. (shrink)

v. 1. Ensino secundário e médio -- v. 2. Estudos sobre o ensino primário -- Planejamento educacional e contribuições à educação do futuro.

This article concerns a silver beaker (now at the Residenzmuseum, Munich) decorated with scenes which seem to be related to the Spanish conquest of Mexico. On the basis of stylistic, iconographic and archival evidence the silversmith is here tentatively identified with an Italian-born artist, Stefano Capello, who is thought to have added a decoration to a pre-existing beaker on the eve of the treaty of Cambrai (3 August 1529). Margaret of Austria, aunt of the emperor Charles V, might have given (...) the beaker as a gift to Louise of Savoy, mother of Francis I, king of France. The article argues, relying upon Warburg’s notion of Pathosformeln (formulas of emotion), that in the early 16th century the New World was perceived and made familiar through an Old World idiom, based on visual formulas taken from classical antiquity and mediated by the Italian Renaissance. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The Heirs of Plato: A Study of the Old Academy (347–274 BC)Carlos SteelJohn M. Dillon. The Heirs of Plato: A Study of the Old Academy (347–274 BC). Oxford: Clarendon Press, 2003. Pp. x + 252. Cloth, $65.00.When Plato died, in 347 BC, he left behind not only the collection of philosophical dialogues we still read with admiration, but also a remarkable organization, the "Academy," wherein his students (...) continued the discussion he had initiated. Dillon's latest book is an attempt to recreate the intellectual climate in the Academy during the first generations after Plato's death, the "Old Academy," called thus to distinguish it from the "New Academy," which started with Arcesilaus in the mid 270's, who abandoned doctrinal speculations for a sceptical stance. Given the elusive nature of the dialogues, the interpretation of Plato's philosophy has been controversial from the beginning. Therefore, scholars always have been eager to know in which direction Plato's first successors—Speusippus, Xenocrates, Polemo—took the Academy; thus they hoped to find some justification for their own interpretation of Plato. Unfortunately, our information on the doctrines of Plato's first successors is scarce. Browsing through the fragments collected by scholars, one may be tempted to conclude that it is not such a great disaster that most texts of the Old Academy have been lost. For it seems that the Academy after Plato was leaning towards a rather esoteric metaphysical speculation about the first principles, which makes us lament on what has become of the philosophical heritage of Plato, a genius fallen into the hands of epigones. One gets the impression that the original and refreshing philosophical contributions came from outside the Academy, from the Lyceum founded by Aristotle and continued by Theophrastus, and later from Epicurus and Zeno and their new schools, which will dominate the Hellenistic period. This, however, is not the view of Dillon: "It will be the thesis of this book that Speusippus and Xenocrates set the agenda for what was to become, over the succeeding centuries, the intellectual tradition which we call Platonism" (v). Even early Stoicism is, in Dillon's view, a "development and formalization of contemporary Platonism" (235).In an introductory chapter Dillon discusses the location and juridical structure of the Academy and gives a general survey of the main doctrines of the school. The following three chapters present the lives, work and thought of the first heads of the Academy; a final chapter is devoted to some minor members of the early Academy. The book concludes with a short epilogue on Arcesilaus and the reasons for his turn to scepticism. Dillon is an [End Page 204] excellent writer who knows how to tease out and expound the most abstruse philosophical doctrines in a captivating way, mixing, as he does here, biographical anecdotes and witty comments with a sharp analysis of arguments and a speculative reconstruction of lost doctrines. I doubt, however, whether this book will become such a classic as his celebrated The Middle Platonists (Ithaca, 1977).My first worry is anticipated by Dillon himself: "This is perforce a rather speculative book, and no doubt it will be criticized for that" (vii). Dillon defends himself against this critique: I have tried, he says, "to put the most favourable construction on the evidence available to us," his assumption being that the figures he is dealing with "were not philosophical imbeciles"(vii). My reservations are not about Dillon's attempt to construct a coherent doctrine using all relevant information on an author, but about his method of reconstruction, in particular his speculation and his preference for often questionable later material to fill the gaps in our information. "With a good deal of speculation, our exiguous information on Polemo's philosophical position can be fleshed out somewhat" (176). Thus, in his exposition of Speusippus's doctrine of the first principles, Dillon does not start from Aristotle, considering him too biased, but from chapter 4 of Iamblichus's treatise De communi mathematica scientia. In this Neo-Pythagorean treatise, Speusippus is not even mentioned. Even if there are arguments, as Dillon believes, to attribute the doctrine of Chapter 4 to Speusippus, one should... (shrink)

In Summa log., I, 5-8 and Quodlib., V, 10-11 Ockham formulates the semantic that lies behind the syntactical distinction between abstract and concrete names and describes the different modes of signification corresponding to them. Sometimes concrete and abstract names stand for different things. For example, 'whiteness' signifies a quality inhering in a subject, whereas 'white' signifies the subject exhibiting that quality and, obliquely, the quality itself. There is a temptation to conclude from such cases that all abstract and concrete names (...) function in the same way. This interpretation, however, seems to imply a 'Platonic' ontology by accepting the existence of universal forms in re. To avoid this conclusion, O. contends that, in the category of substance, abstract and concrete terms are synonymous and simply signify the same thing. Thus nothing is signified by the term ' man' which is not also signified by 'humanity' and vice versa. If we do not take into account that abstract terms may incorporate some syncategorematic elements not included in concrete terms, we must grant that the proposition „man is humanity” is literally true, and we have to reject propositions such as „humanity is in man” or „Socrates is man by his humanity”. For this individual cannot be understood as a bare substrate sustaining a universal essence. Nevertheless, even though this is true from a philosophical standpoint, secundum veritatem fidei it would be false to say that ' man' and ' humanity' are synonymous. As a matter of fact, in theological language these terms can stand for different things. Here a distinction is made between 'humanity' signifying human nature and 'man' which signifies the same nature but connotes also something about the sustenance of that nature. This distinction must be rejected in the case of Socrates. Here humanity coincides with man so that the proposition „Socrates is a substrate sustaining a human nature” is false. But the same proposition is true when it is said of the divine Person united with the human nature in Christ. It follows that O. accepts in theology a semantic distinction between abstract and concrete names and also the existence of an essence different from the subject, both of which he opposes from a philosophical standpoint. He schrinks from applying his original logical insights to the theological dogmas which are often formulated in terms that involve a realistic ontology of essences. But even when he limits the results of his semantic analysis to the realm of pure philosophy, it seems difficult to maintain the equivalence in signification of abstract and concrete names. (shrink)

This chapter contains sections titled: God and the primordial causes God and the world: theophany “Man: how great a thing and great a name, the image of divine nature” (V, 821C) Last things Eriugena in his time and beyond.